

Virology | The Institute of Human Virology Programs
Virology
Our School of Medicine nucleates a large number of distinguished virologists, with primary and secondary appointments in the Department of Microbiology and Immunology. Among these, Drs. DeVico, Gallo, Garzino-Demo, Kamin-Lewis, Lu, Lukashevich Lewis, Melikian, Pauza, Popovic, Salvato and Reitz work at the adjacent IHV, and study the molecular mechanisms of infection and pathogenesis caused by
primate (HIV and SIV) and rodent retroviruses, human herpes type 8 viruses, paramyxoviruses and arenaviruses viruses. The IHV is actively pursuing vaccine development for these viral pathogens (for detailed description of research at IHV see letter to Prospective Students from Dr. Gallo). Dr. Laure Aurelian studies mechanisms of viral latency and pathogenesis of Herpes Simplex virus, and is developing HSV vaccines. Dr. Feldman studies mechanisms of oncogenesis by RNA tumor viruses and is developing animal models of leukemogenesis by sequential targeting of oncogenes to hematopoietic stem cells in vivo. Dr. Zhao studies the role of Vpr in HIV pathogenesis, as well as virus-host interactions and their roles in cell cycle G2/M regulation, apoptosis and host innate antiviral responses.